主要研究方向为无机纳米材料与生物材料在生物传感器中的应用，旨在构建高性能的表面增强拉曼光谱生物传感器用于抗原抗体、DNA、抗生素以及环境污染物等的研究。

项目：食品及农产品中危害残留物快速检测技术四川省青年科技创新研究团队-四川省科技计划项目专项资金

发表SCI论文：

1. Yi He*，Zhiyou Zeng, Yongguo Cao, Xiao Zhang, Caijun Wu*, Xiaojun Luo*. Ultrasensitive SERS biosensor based on Zn2+ from ZnO nanoparticle assisted DNA enzyme amplification for detection of miRNA. Analytica Chimica Acta 1228(2022)340340.

2. Xiaojun Luo*, Weiling Yue, Shutong Zhang, Haopeng LIu, Zhinan Chen, Ling Qiao, Caijun Wu, Panjie Li* and Yi He*. SERS-CoV-2 proteins monitored by long-range surface plasmon field-enhanced Raman scattering with hybrid bowtie nanoaperture arrays and nanovavities. Lab on a Chip 2023,23,388-399. 

3. Xiaojun Luo, Shutong Zhang, Zhichao Xia, Rui Tan, Qiuju Li, Ling Qiao, Yi He*, Guoqi Zhang*, Zhihong Xu.* Analytica Chimica Acta 1241 (2023) 340803.

4. Yi He*, Xiangjian Liao, Haonan Wu, Jialiang Huang, Yi Zhang, Yanyu Peng, Zhen Wang, Xin cao, Caijun Wu*, Xiaojun Luo*. A controllable SERS biosensor for ultrasensitive detection of miRNAs based on porous MOFs and subject-object recognition ability. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 289 (2023) 122134.

5. Weiling Yue, Zhichao Xia, Zhiyou Zeng, Zhinan Chen, Ling Qiao, Panjie Li*, Yi He*, Xiaojun Luo*. In situ Surface-Enhanced Raman Scattering Detection of a SARS-CoV-2 Biomarker Using Flexible and Transparent Polydimethylsiloxane Films with Embedded Au Nanoplates. ACS Applied Nano Materials, 2022, 5, 12897-12906.

6. Xiaojun Luo*, Ling Qiao, Zhichao Xia, Jiaming Yu, Xiaozhou, Wang, Juhong Huang, Chang Shu, Caijun Wu*, Yi He*. Shape- and Size-Dependent Refractive Index Sensing and SERS Performance of Gold Nanoplates. Langmuir 2022, 38, 6454-6463.

7. Minghang Jiang,* Mengfei Zhu, Mengjun Wang, Yi He, Xiaojun Luo, Caijun Wu; Liyun Zhang, Zhong Jin,* Review on Electrocatalytic Coreduction of Carbon Dioxide and Nitrogenous Species for Urea Synthesis, ACS Nano, 2023, 17, 3209-3224.

8. Xiaojun Luo, Rui Tan, Qiuju Li, Jiaxin Chen, Yalin Xie, Jiayi Peng, Mei Zeng, Minghang Jiang,* Caijun Wu,* Yi He,* High-sensitivity long-range surface plasmon resonance sensing assisted by gold nanoring cavity arrays and nanocavity coupling. Phys. Chem. Chem. Phys. 2023. DOI: 10.1039/d2cp05664j 

9.Yi He, Xia Yang, Ruo Yuan, and Yaqin Chai, “Off” to “On” Surface-Enhanced Raman Spectroscopy Platform with Padlock Probe-Based Exponential Rolling Circle Amplification for Ultrasensitive Detection of MicroRNA 155. Anal. Chem. 2017, 89, 2866−2872. 

10. Yi He, Xia Yang, Ruo Yuan, and Yaqin Chai, Switchable Target-Responsive 3D DNA Hydrogels As a Signal Amplification Strategy Combining with SERS Technique for Ultrasensitive Detection of miRNA 155. Anal. Chem. 2017, 89, 8538−8544.

11.Yi He, Yue Wang, Xia Yang, Shunbi Xie, Ruo Yuan, and Yaqin Chai, Metal Organic Frameworks Combining CoFe2O4 Magnetic Nanoparticles as Highly Efficient SERS Sensing Platform for Ultrasensitive Detection of N‑Terminal Pro-Brain Natriuretic Peptide. ACS Appl. Mater. Interfaces 2016, 8, 7683−7690.

12.Yi He, Shunbi Xie, Xia Yang, Ruo Yuan, and Yaqin Chai, Electrochemical Peptide Biosensor Based on in Situ Silver Deposition for Detection of Prostate Specific Antigen. ACS Appl. Mater. Interfaces 2015, 7, 13360−13366.

13.Yi He, Xia Yang, Ruo Yuan, and Yaqin Chai, A novel ratiometric SERS biosensor with one Raman probe for ultrasensitive microRNA detection based on DNA hydrogel amplification. J. Meter. Chem. B 2019, 7, 2643--2647.

承担本科生分析化学、分析化学实验等教学工作。